Questions? +1 (202) 335-3939 Login
Trusted News Since 1995
A service for ipo industry professionals · Monday, December 10, 2018 · 470,700,770 Articles · 3+ Million Readers

Global Respiratory Drugs Market 2017-2023: Global Revenue from the Respiratory Market is Forecast to Increase from $30.9 Billion in 2016 to $41.3 Billion in 2023, at a CAGR of 4.23%

/EIN News/ -- Dublin, Dec. 07, 2017 (GLOBE NEWSWIRE) -- The "Global Respiratory Drugs Market to 2023 - A Changing Therapeutic Landscape as Key Patents Expire and Biologics, Targeted Therapies and CFTR Modulators for Asthma and Cystic Fibrosis Treatment Emerge as Market Growth Drivers" report has been added to Research and Markets' offering.

Global Respiratory Drugs Market to 2023 provides the following analysis:

  • Provides introduction to respiratory disorders, including disease epidemiology, symptoms, pathophysiology, co-morbidities and complications and prognosis. Methods of diagnosis are also provided. The chapter concludes with an analysis of the general treatment options.
  • Provides overview of the marketed products landscape, including product profiles of key marketed products and revenue projections for each of these drugs.
  • Analyzes the respiratory disorders pipeline, detailing, among other parameters, drug distribution by stage of development, molecule type and molecular target, plus an analysis of the key indications in the pipeline: leukemia, lymphoma and myeloma. The clinical trial landscape is also examined, with an emphasis on trends in clinical trial failure rates, duration and size.
  • Presents forecast projections to 2023 on a global level, with forecasts provided for the US, plus aggregate revenue forecasts of the top five EU markets (the UK, France, Germany, Italy and Spain) and Japan. Additionally, revenue forecasts for the major product categories and key players are provided.
  • Assesses the company landscape, with an analysis of the key players, the types of company involved in this therapy area, and whether this therapy area comprises a large proportion of each company's pipeline portfolio and total revenues.
  • Analyzes trends in co-development and licensing deals, relating to respiratory disorder products. Some of the most prominent deals are discussed in detail.

Respiratory disorders, which affect components of the respiratory system such as the lungs and airway, are a broad range of chronic diseases with a variety of underlying causes, ranging from inherited mutations to pathological inflammation. The respiratory disorders market is dominated by long-acting beta-agonist (LABA) and long-acting muscarinic antagonist (LAMA) therapies for chronic obstructive pulmonary disease (COPD) and asthma. These drugs stimulate the muscles surrounding the bronchial tubes to relax and open the airways.

Recently approved products in COPD include multiple LABA/LAMA fixed-dose combinations, some of which are forecast to generate over $1 billion by 2023, and include GlaxoSmithKline (GSK)'s triple-combination therapy (fluticasone furoate plus umeclidinium bromide plus vilanterol trifenatate). The approval of novel biologics in the asthma market, including interleukin (IL)-targeting Nucala (mepolizumab), marketed by GSK, is also forecast to have a strong commercial impact on the market. Notable drivers of growth in the cystic fibrosis (CF) market are the recently approved disease-modifying therapies Kalydeco (ivacaftor) and Orkambi (lumacaftor/ivacaftor), both from Vertex.

Respiratory therapy area consists of indications that affect the lungs, bronchi, trachea, larynx, pharynx and nose in different ways, such as the scarring of lung tissue or the excessive production of mucus. Respiratory disease most commonly results in breathing difficulties, which can lead to disruptions in sleep, wheezing, anxiety and stress. In more severe cases shortness of breath (dyspnea) can limit physical activity, affecting both the quality of life and life expectancy of sufferers. The cause of respiratory disorders varies significantly across each indication and includes factors such as environment, occupation, genetic predisposition and aging.

In 2016, GSK was the leading company in terms of revenue generated from respiratory disorder products, accounting for 30.3% of the market, while Vertex had a small market share of 5.3%. However, the emergence of cystic fibrosis transmembrane conductance regulator (CFTR) modulating therapies, which are considered disease-modifying therapies for CF, an indication which has traditionally only had symptomatic treatments, is set to have a substantial clinical and commercial impact. There are only two of these products on the market, Orkambi and Kalydeco, both of which were developed by Vertex.


  • Global revenue from the respiratory market is forecast to increase from $30.9 billion in 2016 to $41.3 billion in 2023, at a compound annual growth rate of 4.23%. What is driving this growth?
  • The leading companies in terms of market share are GSK, AstraZeneca and Boehringer Ingelheim. Which of these are forecast to experience the largest growth?
  • There have been many new approvals in the therapy area. Which drugs will achieve blockbuster status?
  • The market has been dominated by ICS/LABA therapies. What classes of drugs dominate the market and which will dominate over the forecast period?
  • There are 930 respiratory products in the pipeline. What molecular targets are most abundant in the pipeline and what role will pipeline product approvals play in market growth?
  • Respiratory disorders clinical trials have an overall attrition rate of around 70%, what can companies do to maximize their chance of success?

Key Topics Covered:

1 Table of Contents

2 Introduction
2.1 Therapy Area Introduction
2.2 Symptoms
2.3 Diagnosis
2.3.1 Asthma
2.3.2 Chronic Obstructive Pulmonary Disease
2.3.3 Idiopathic Pulmonary Fibrosis
2.3.4 Cystic Fibrosis
2.4 Etiology and Pathophysiology
2.4.1 Asthma
2.4.2 Chronic Obstructive Pulmonary Disease
2.4.3 Idiopathic Pulmonary Fibrosis
2.4.4 Cystic Fibrosis
2.5 Epidemiology
2.5.1 Asthma
2.5.2 Chronic Obstructive Pulmonary Disease
2.5.3 Idiopathic Pulmonary Fibrosis
2.5.4 Cystic Fibrosis
2.6 Prognosis and Disease Staging
2.6.1 Asthma
2.6.2 Chronic Obstructive Pulmonary Disease
2.6.3 Idiopathic Pulmonary Fibrosis
2.6.4 Cystic Fibrosis
2.7 Treatment
2.7.1 Asthma
2.7.2 Chronic Obstructive Pulmonary Disease
2.7.3 Idiopathic Pulmonary Fibrosis
2.7.4 Cystic Fibrosis

3 Key Marketed Products
3.1 Overview
3.2 Advair - GSK
3.3 Symbicort - AstraZeneca/Astellas
3.4 Spiriva - Boehringer Ingelheim
3.5 Xolair - Roche/Novartis
3.6 Ventolin - GSK
3.7 Pulmicort - Astra Zeneca
3.8 Orkambi - Vertex
3.9 Relvar/Breo Ellipta - GSK
3.10 Singulair - Merck & Co.
3.11 Esbriet - Roche
3.12 Kalydeco - Vertex
3.13 Conclusion

4 Pipeline Landscape Assessment
4.1 Overview
4.2 Pipeline Development Landscape
4.3 Molecular Targets in the Pipeline
4.4 Clinical Trials
4.4.1 Failure Rate by Stage of Development, Indication, Molecule Type and Molecular Target
4.4.2 Clinical Trial Duration by Stage of Development, Indication, Molecule Type and Molecular Target
4.4.3 Clinical Trial Size by Stage of Development, Indication, Molecule Type and Molecular Target
4.4.4 Aggregate Clinical Program Size by Stage of Development, Indication, Molecule Type and Molecular Target
4.5 Assessment of Key Pipeline Products
4.5.1 Ivacaftor and Tezacaftor - Vertex
4.5.2 (Fluticasone Furoate plus Umeclidinium Bromide plus Vilanterol Trifenatate) - GlaxoSmithKline/Innoviva
4.5.3 Dupixent - Regeneron Pharmaceuticals/Sanofi
4.5.4 Benralizumab - AstraZeneca/Medimmune
4.5.5 Tralokinumab - AstraZeneca
4.5.6 PT010 (Budesonide plus Formoterol Fumarate plus Glycopyrrolate) - AstraZeneca/Pearl Therapeutics
4.5.7 Conclusion
4.6 Conclusion

5 Multi-scenario Market Forecast to 2023
5.1 Overall Market Size
5.2 Generic Penetration
5.3 Revenue Forecast by Molecular Target
5.3.1 G Protein-Coupled Receptors
5.3.2 Immune/Inflammatory Mediators
5.3.3 Transcription Factors
5.3.4 Signal Transduction
5.3.5 CFTR Modulator

6 Company Analysis and Positioning
6.1 Revenue and Market Share Analysis by Company
6.1.1 GlaxoSmithKline
6.1.2 Vertex
6.1.3 AstraZeneca
6.1.4 Roche
6.1.5 Boehringer Ingelheim
6.1.6 Novartis
6.1.7 Teva
6.1.8 Sumitomo Dainippon
6.1.9 Regeneron
6.1.10 Merck & Co.
6.2 Company Landscape
6.3 Marketed and Pipeline Portfolio Analysis

7 Strategic Consolidations
7.1 Licensing Deals
7.1.1 Deal by Region, Year and Value
7.1.2 Deals by Stage of Development and Value
7.1.3 Deals by Molecule Type and Molecular Target
7.1.4 Table for Licensing Deals Valued Above $100m
7.2 Co-development Deals
7.2.1 Deals by Region, Year and Value
7.2.2 Deals by Stage of Development and Value
7.2.3 Deals by Molecule Type, Mechanism of Action and Value
7.2.4 Table for Co-development Deals Valued Above $100m

8 Appendix
8.1 Bibliography
8.2 All Pipeline Drugs by Phase
8.2.1 Discovery
8.2.2 Preclinical
8.2.3 IND/CTA-Filed/Phase 0
8.2.4 Phase I
8.2.5 Phase II
8.2.6 Phase III
8.2.7 Pre-registration
8.3 Abbreviations
8.4 Methodology

Companies Mentioned

  • Astra Zeneca
  • Astellas
  • Boehringer Ingelheim
  • GlaxoSmithKline
  • Merck & Co.
  • Novartis
  • Regeneron
  • Roche
  • Sumitomo Dainippon
  • Teva
  • Vertex

For more information about this report visit

                    CONTACT: Research and Markets
                             Laura Wood, Senior Manager
                             For E.S.T Office Hours Call 1-917-300-0470
                             For U.S./CAN Toll Free Call 1-800-526-8630
                             For GMT Office Hours Call +353-1-416-8900
                             Related Topics: Genomics, Respiratory Drugs, Respiratory Drugs, Biopharmaceuticals , Asthma Drugs 

Primary Logo

Powered by EIN News

EIN Presswire does not exercise editorial control over third-party content provided, uploaded, published, or distributed by users of EIN Presswire. We are a distributor, not a publisher, of 3rd party content. Such content may contain the views, opinions, statements, offers, and other material of the respective users, suppliers, participants, or authors.

Submit your press release